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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee8c7b33788868383a2163824050c33ccc8c6b2967f7357ddd8a60962d5d4086' 
  AND token = 'u0GEm6DjuO5z5/+A+Mt5t45Gza62uqZgvpA19oeHUvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}