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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cd12d1a20beefadacc7a741bc83453f0460fad62a8a4a7f6fcf17739f05a567' 
  AND token = 'Sh0COkFSpSHvi5fVtAoBSl/h+rrnI2MPGRErCBtSggw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}