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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '070227f76349005f595b29e6e2203fd148ae3552b08edc8d805970034d2404cf' 
  AND token = '0J+CaGWOu5b8bSKMdEYrTVYSfjHZ51HI16UtbCNxRag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}