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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acd9a980cc627b82a3129d99e837da0326b2dd72203007c9acbff7dfe1fffc06' 
  AND token = 'i6XCu0MW4Y8/HIRNTOq3/tqvls3g48JzBtG2No0lQJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}