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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c10192bea3cdda7a3a7adf7aff7f1d5a8e469f5ceacc2dffc88f81653df31c9' 
  AND token = 'NvQMwTyeoC5ZDr2BJthL9OWMBkv3WtYiCP77w5RTO/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}