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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43f69e03e9dae9bd2896d9a60fb95938c6dea265c11912021c5a5cd52d9d8c86' 
  AND token = 'zX9/WAIDEqj1VhZfmefJdfZy23AAPCVYcBvny/K683o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}