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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e217164d6d86c8cda1760b16cc83e864e7a44256ce99f92d4a8a5d2aa24a669' 
  AND token = 'Loiq1G2kiQcG/fX5LT6SYSvU4YfQiDctiAx/y2Z1q4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}