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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b46d74748725ba8d567324d6db607c4030c1f396d787fc29755fe8a015bcb488' 
  AND token = 'MG8gDgKZFK2AHOAzOQ3Go/+L34BdrHBNzQffsXiOt0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}