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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '887b56c424b157e41924c3aaa1d38406dc70aa33e274f9f832ac934308d72671' 
  AND token = 'DUZstRaIGMCmqSEABEBENI9PT3wI7l+VJNTYLR/a2Lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}