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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caa77c9245e481a374231f4225c75020f917c3c5017517b5b7a412a20b5c7331' 
  AND token = 'TqNO4szO7hG77Mj8zG16psM5+3gM6h1hiZ+Oh4VEjbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}