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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4263a016e4fa46cbacbf4df35f8a49b56337500b812f098d6e12ff4ccfc0b80f' 
  AND token = 'tWyJ9udEZzE/ZwY1xf7iHfMDwC23xa7L8ovNFU5e02Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}