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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80598181ab176f2517ec5ea3ef142720f780f997f97776d63c31b3f3731d6b6c' 
  AND token = 'vI9Ck6Pf2ECUOfhwvwZ9BfaS0HEXwCj/wlYpPb28ih4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}