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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a27a090f242f8acaec3311b01e78c37dae73282888db5e7b89d44d793b7b201' 
  AND token = '/SGvToASwQ+2i9VLv22nEA1HIujNbU2A11P63VsUJCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}