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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cb6fa85e2688c2400e0cdcbf7cf719300963af1b813851f77d5615fedbd5b1b' 
  AND token = 'd6jGRsDHi41gqwrd6lD3vWrBmeBVxuXC/bsLkmfcNgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}