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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0d6296b4715286613a7bfd4bd16d1355131d4c1d8286ed2425d01f82256dfe4' 
  AND token = 'XrkGaX8vxZ0F6VbhACv9NKg3ESFmlZVPkmNKEd/ENo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}