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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fea26064dc505bf27ca92a0516686b61e37846b60b12384a96b2bed193f36a6' 
  AND token = 's1KEawLqYAeq32Tu1sXBQoqatR+hiWAtQZ2107vOY7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}