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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bd949e0afd173a0b3265cdfc911959f4eb4e34866adcb19c71d1d5ef05d39b5' 
  AND token = 'RpwRk6ZmpFLkG7mpJTK0rYiK+kQjjPo37M8NY3W7HSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}