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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '465bc268604a0d06cbbe94d6b6a2e0485f2564fba89a97e0f61cb6f1e1bbadb8' 
  AND token = 'Hz9KwU9owjG8xePsttojDnNA5N99UTInDJlPxlNjbAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}