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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd900b8c3ffb8cf204df805f3892e585b27196a9ab4f3dc2504d1b3e808d067dd' 
  AND token = 'zDOAp4t+czMyTYTNzhKbN2m/CYyoUm++uz4BSZIJIoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}