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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37b2ed8c8a6598eebf8fe7230993b039a4c97f888e5c596b7a240bc7935e27c0' 
  AND token = '+L7FHVmixceZzkTDHjsdG4QgRE1PSz5XsVMZ6064Uzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}