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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0450fc246a1ed80584daab8ee143de55ad03e44e1a530882341e906619f196a3' 
  AND token = 'kUIWmsQfkBH7AMltZxbKj2i10n5Za2+4NAjzM9S8kaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}