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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eed0284811169000e18870ad68b8b838ae127fe50f570b84efc65c8b1652fd50' 
  AND token = 'ofYrz+IvhOLAktW/JQ84Ssyby40daEa6dPMpvvl7VIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}