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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de7d18f53463c8759bb28f8960d9fa735d00691c85efab476e99060f7a9e8bea' 
  AND token = 'mCIbM4/RnOh4ogsiFWJup5rmitnZX3sxCVkPQs4Es30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}