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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a148b95ae557dbb8c4de3a099ad63a79fbc0cf28a38ddc46948734b8c8c544e' 
  AND token = 'zMkY0siS3+7ZcpOKS43GptUymKsYSAszpPB/EVGG3pw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}