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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a63453c215e9ff04e493ff11db2f2a4c04e783a3b8050d1cd4b2afbd34172db7' 
  AND token = 'NVkMt0B0AdWZd0/m7pXFqbSpPWhdQ73T8XB4wXV14A0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}