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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b33d3a3b1d6530b3e95fd650b1fc54d8c570a8e1e95cdb0a21d3172d34d208b7' 
  AND token = 'qNpeqAy94Ky4E3eiDHF53WOKBemOIAeFv+Q7hkZQSYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}