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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c8927984c0ac5216a52e4d808a2725a241aff4358c5b5bee19fe5301f8e7c22' 
  AND token = 'ahB5xmNof1CcTu02YJ6i/4X7wWP8PWZYo8vEzjf+SbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}