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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb15e4bcb314527714f3a552b82f364cf87d1cefd18516531fcf4f1aa75a23a2' 
  AND token = 'VaSCrRR9FP/3cQPZ7qwjhpVnxVQlZ7YbnFN78rk4apg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}