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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a0d3f19aabaeba149653f65f833b80ff1c251ab6c50ab7b831de722a395dad8' 
  AND token = 'e/knoC+qHN05K009sMIA1F44xk/KPLeVZmPVaQo/KXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}