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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24ea8fd09b79167b83c2aac81cee27511833b328e10e9cf6b52b70ee9e614854' 
  AND token = '1z9VlXtH37U2e9dtbqG1IDQXxJNrcwJXUzyopkN4p0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}