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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e54ff333d7021b146a9a692cbbf4936fb00d56aae95b9d3fb10e29ed4c0bae16' 
  AND token = 'xLf2BtBdMbIhKQGHQ79KmHuadNgd0f7aXCEhU66C+0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}