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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d49f69b0067b0d7c8294df45f7abfddb995140aad0e0cb5fa008b2c8974b28d' 
  AND token = '4Ikw0iCFvba36+zYAwCSEeuRXvJ1oSzWFkNvhRxK0O4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}