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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '431b87a7932e222965a6092561c726a4918948080ebb438005f34fec8b34381d' 
  AND token = 'xakmqVsn9bGYTL7TRI+oucIGjDu7J7tqpL7kdxnQWgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}