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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '418cb21f6ad4acc380ef92d68ad2e93a1a36a7abacb36e9059f6f32761a88e1c' 
  AND token = 'WhpVAbVDRYZrjgiHX4z8d06Xvkl9Ic0p+hpew9YdxRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}