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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3214b8ee37b4a245a744008fb540d913251811ea712b1d61f1971d01c90265fb' 
  AND token = 'zIKHM21TtAzN6dB+oC4slGfvZlBjRlaRGSqDyWC2FtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}