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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bba6846720b04e29cce050c1166f928b37a2de6704bcc62497edc77391825751' 
  AND token = 'MS7zxobRPVjV1xqnUiVoj96zdFwS6qA09uLXy9FkwrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}