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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64177e2b05cdbf6fc07d7cf45106ffbdf2429c8ed990abd419f612b754f03956' 
  AND token = '3iFmxG6D+9CC4dDliSnCTm15BvIy9ZwA1z+2s8zJkFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}