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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8681a8573cd22f63ca6c404a93b44b9005b5f7dd3c1a4f08e737f64e2b53bef' 
  AND token = 'VkEyQIO9a5HogtXAovZ4yl30wwpHaU6PgN5wgcFdPzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}