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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '381a1ce1d5c7d4c680c5d6eec2018ed2e90cb73bcec772d0b64d4d8de9a89f87' 
  AND token = 'WOw6gCIaBPrHJU+D0b+epa40An0nreYiJ0/o5Y3ed3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}