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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f83c4a82c149a3a712f7a37cf427f00c1a55e4525fbf526a8ed27ea76003564' 
  AND token = 'ORMZG79ZSBn9oC2fpFiDTXAMWUTpGXM0duNDnN1xd60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}