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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dc4d7f166aee16d667a14c60b2b93b28764785291e591b01bdba9eeb54e5f9a' 
  AND token = '6U+hxRBfhKX+3gG1MPqwkS2xaCIDRJJb0nt02kfW9cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}