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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ca050022591ce3247203aa0c0b49dfc00c181209e8f4d13f96ade44cb0332a4' 
  AND token = 'Ql52LC1+C+dLD2+pJCv4Q/IBHbsq8nbIPyjOiIBDD/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}