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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34e9469b6dc277fe0fb1cabdf7fd63493d6457c0dd95afb5820f3aff038066c9' 
  AND token = 'FwjYg344RGEnExF+kA5UL4FenVV1NubEiFceTyNeeOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}