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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab01120000b4deece9982e8b5a0e9215eda5308724be39dc447812a551f4a7f5' 
  AND token = 'vopWm0wtK9TMEI/pH0T3jq0WzXfU7r3wM+/PRDX+Nlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}