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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca9c40455509f8e0043f627e9d7dfca3feb53d40721050d8e1bd88a1f8cb2e9b' 
  AND token = 'J4XU9aoUAtNH95FNDB+mTym32eZb1BZ+4/6KDnjQkUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}