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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fe8f567525676e3d147d08cb5c755bea071f9468b7f4ce20979500471b725c6' 
  AND token = 'MMuLK2hFEZvJSPS84pfFvaA1R6kbLp7fQcKsxkPLP7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}