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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad2097e06f3e76108ce4db6d79b790dcb09e9b24cb0ced68219d239ae402f9c4' 
  AND token = 'zIu+2y4phFZcpwt2n0o5LqLNrsw6PkOVVdXvU/TkN9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}