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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '853200ea46e1beb485c4262c577cbdcad4697d30372aa40dc66fa5545190ab78' 
  AND token = 'Zs1es6uOgZEsSGwB9rYWwGNkRV64Ol8hehHmJW0RZdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}