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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f7f89075900fa1a83c654d016c7e1fdc0973a166a642cf18e7991e3e7fd80e' 
  AND token = '4SDcm5XV7p027xkhqBvbDIQV4lSwI8yeyQiIuXhVIEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}