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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ca41bd5a5adfbb357d0372098911af8a1d3d9830c2b16531ce6ede63bf8424' 
  AND token = '26reY5bDsrfjXcPcOq/0jPzmU5veU277aTfljULbLKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}